cFLIP Rabbit Polyclonal Antibody (CAB2555)
- SKU:
- CAB2555
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | cFLIP Rabbit Polyclonal Antibody |
SKU: | CAB2555 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-240 of human cFLIP (NP_003870.4). |
Sequence: | VSDY RVLM AEIG EDLD KSDV SSLI FLMK DYMG RGKI SKEK SFLD LVVE LEKL NLVA PDQL DLLE KCLK NIHR IDLK TKIQ KYKQ SVQG AGTS YRNV LQAA IQKS LKDP SNNF RLHN GRSK EQRL KEQL GAQQ EPVK KSIQ ESEA FLPQ SIP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CASH; FLIP; MRIT; CLARP; FLAME; cFLIP; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1 |
Positive Sample: | Jurkat,Mouse liver,Mouse heart,Rat liver,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, ripoptosome |
Calculated MW: | 55kDa |
Observed MW: | 28kDa/55kDa |
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
Purification Method: | Affinity purification |
Gene ID: | 8837 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |