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CFL1 Monoclonal Antibody [PAT1C1AT] (CPAB0537)

SKU:
CPAB0537
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT1C1AT
Applications:
WB
ELISA
€149
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Description

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CFL1 Monoclonal Antibody [PAT1C1AT] (CPAB0537)

The CFL1 Polyclonal Antibody (CPAB0537) is a valuable tool for researchers studying the CFL1 protein, a key regulator of actin dynamics and cell migration. This antibody, generated in rabbits, is highly specific to human CFL1 and has been validated for use in Western blot applications. By targeting the CFL1 protein, this antibody allows for precise detection and analysis of CFL1 expression in a variety of cell types, making it ideal for studies focusing on cytoskeletal dynamics, cell motility, and cancer metastasis.CFL1, also known as Cofilin-1, plays a crucial role in regulating actin filament turnover and organization, which is essential for a wide range of cellular processes, including cell migration, division, and shape changes.

Dysregulation of CFL1 has been implicated in various diseases, such as cancer, neurodegenerative disorders, and cardiovascular diseases. Therefore, investigating the function and expression of CFL1 is essential for understanding the underlying mechanisms of these conditions and developing targeted therapies.Overall, the CFL1 Polyclonal Antibody (CPAB0537) offers researchers a reliable tool for studying CFL1 biology and its involvement in cellular processes and disease pathology. Its specificity, sensitivity, and reproducibility make it a valuable asset for advancing research in cell biology, cancer biology, and therapeutic development.

Product Name:CFL1 Antibody
Product Sku:CPAB0537
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CFL1 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CFL1 amino acids 1-166 purified from Ecoli.
Clone:PAT1C1AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:CFL1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:Cofilin is a family of actin-binding proteins which disassembles actin filaments. It is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Synonyms:CFL-1, CFL1, Cofilin1, Cofilin-1, Cofilin non-muscle isoform, 18 kDa phosphoprotein, p18.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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