The CFHR3 Polyclonal Antibody (CAB7775) is developed for research purposes involving CFHR3, a key regulator of the complement system. This antibody, produced in rabbits, exhibits strong reactivity towards human samples and is validated for use in various applications including Western blotting. By targeting the CFHR3 protein, this antibody enables precise detection and analysis in different cell types, making it an ideal tool for investigations in immunology and related fields.CFHR3, a complement factor H-related protein, plays a vital role in regulating the complement cascade and immune response. Dysregulation of CFHR3 is associated with various autoimmune diseases, inflammatory conditions, and renal disorders.
Research into the function of CFHR3 is essential for understanding the underlying mechanisms of these diseases and for developing targeted therapies that modulate the complement system.By utilizing the CFHR3 Polyclonal Antibody (CAB7775), researchers can gain valuable insights into the role of CFHR3 in immune modulation and disease pathogenesis. This antibody serves as a valuable tool for studies aimed at uncovering the molecular basis of complement-related disorders and exploring novel therapeutic strategies in immunology and beyond.
Product Name:
CFHR3 Rabbit Polyclonal Antibody
SKU:
CAB7775
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2).
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10878
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Rat liver, using CFHR3 Rabbit pAb (CAB7775) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
