CFHR1 Rabbit Polyclonal Antibody (CAB2743)
- SKU:
- CAB2743
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CFHR1 Rabbit Polyclonal Antibody |
SKU: | CAB2743 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 151-330 of human CFHR1 (NP_002104.2). |
Sequence: | PTVQ NAHI LSRQ MSKY PSGE RVRY ECRS PYEM FGDE EVMC LNGN WTEP PQCK DSTG KCGP PPPI DNGD ITSF PLSV YAPA SSVE YQCQ NLYQ LEGN KRIT CRNG QWSE PPKC LHPC VISR EIME NYNI ALRW TAKQ KLYL RTGE SAEF VCKR GYRL SSRS HTLR TTCW DGKL EYPT CAKR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | H36; CFHL; FHR1; HFL1; HFL2; CFHL1; FHL-1; FHR-1; H36-1; H36-2; CFHL1P; CFHR1P; CFHR1 |
Positive Sample: | LO2,HeLa,NCI-H460,Mouse liver,Mouse lung,Mouse heart,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 38kDa |
Observed MW: | 43kDa |
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
Purification Method: | Affinity purification |
Gene ID: | 3078 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |