The CFHR1 Polyclonal Antibody (CAB2743) is a valuable tool for researchers studying the CFHR1 protein, a crucial factor in the complement system. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in a variety of research applications such as Western blotting.CFHR1, also known as complement factor H-related protein 1, is involved in regulating the complement system, which is essential for immune responses and inflammation. Dysregulation of CFHR1 has been associated with various diseases such as autoimmune disorders, kidney diseases, and age-related macular degeneration.
By using the CFHR1 Polyclonal Antibody, researchers can effectively detect and analyze CFHR1 protein levels in different cell types, aiding in the understanding of its function and potential roles in disease pathology. This antibody is a valuable tool for immunologists, researchers, and clinicians working to uncover the complexities of the complement system and its implications in various health conditions.
Product Name:
CFHR1 Rabbit Polyclonal Antibody
SKU:
CAB2743
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 151-330 of human CFHR1 (NP_002104.2).
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
Purification Method:
Affinity purification
Gene ID:
3078
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CFHR1 antibody (CAB2743) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
