CFD Monoclonal Antibody (CAB21110)
- SKU:
- CAB21110
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | CFD Monoclonal Antibody |
SKU: | CAB21110 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-253 of human CFD (P00746). |
Sequence: | ILGG REAE AHAR PYMA SVQL NGAH LCGG VLVA EQWV LSAA HCLE DAAD GKVQ VLLG AHSL SQPE PSKR LYDV LRAV PHPD SQPD TIDH DLLL LQLS EKAT LGPA VRPL PWQR VDRD VAPG TLCD VAGW GIVN HAGR RPDS LQHV LLPV LDRA TCNR RTHH DGAI TERL MCAE SNRR DSCK GDSG GPLV CGGV LEGV VTSG SRVC GNRK KPGI YTRV ASYA AWID SVLA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | DF; ADN; PFD; ADIPSIN; CFD |
Positive Sample: | U-937,Human plasma |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 27kDa |
Observed MW: | 27kDa |
This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
Purification Method: | Affinity purification |
Gene ID: | 1675 |
Clone Number: | ARC2997 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |