The CFAP53 Polyclonal Antibody (CAB16607) is a valuable tool for research involving CFAP53, a protein involved in cilia and flagella structure and function. This antibody is produced in rabbits and is highly reactive with human samples, making it ideal for use in Western blot applications. By binding to the CFAP53 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it a crucial asset for studies in cell biology and cilia-related diseases.
CFAP53 is known for its role in cilia and flagella assembly and motility, making it a key player in cellular processes such as cell signaling and movement. Research into the function of CFAP53 can provide insights into genetic disorders related to cilia dysfunction, such as primary ciliary dyskinesia and infertility. By understanding the mechanisms of CFAP53, researchers can develop targeted treatments for these conditions, offering hope for improved patient outcomes in the future.
Product Name:
CFAP53 Rabbit Polyclonal Antibody
SKU:
CAB16607
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CFAP53 (NP_659457.2).
This gene belongs to the CFAP53 family. It was found to be differentially expressed by the ciliated cells of frog epidermis and in skin fibroblasts from human. Mutations in this gene are associated with visceral heterotaxy-6, which implicates this gene in determination of left-right asymmetric patterning.
Purification Method:
Affinity purification
Gene ID:
220136
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CFAP53 Rabbit pAb (CAB16607) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
