The CFAP44 Polyclonal Antibody (CAB14539) is a valuable tool for researchers studying CFAP44, a protein involved in cilia formation and function. This antibody, developed in rabbits, specifically targets CFAP44 in human samples and is optimized for Western blot applications. By binding to the CFAP44 protein, this antibody allows for accurate detection and analysis in various cell types, making it an essential component for studies in cell biology and ciliopathies.
CFAP44 plays a crucial role in maintaining cilia structure and function, which are essential for cellular signaling and motility. Dysregulation of cilia has been linked to various diseases, including cystic kidney disorders and respiratory diseases. Understanding the role of CFAP44 in cilia biology is key to advancing research in these areas, potentially leading to the development of targeted therapies for ciliopathies and related conditions.
Product Name:
CFAP44 Rabbit Polyclonal Antibody
SKU:
CAB14539
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-370 of human CFAP44 (NP_001157968.1).
Enables peptidase activity. Involved in sperm axoneme assembly. Acts upstream of or within microtubule cytoskeleton organization. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Implicated in spermatogenic failure 20.
Purification Method:
Affinity purification
Gene ID:
55779
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CFAP44 Rabbit pAb (CAB14539) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
