The Centrin-1 Polyclonal Antibody (CAB3784) is a essential tool for researchers studying Centrin-1, a calcium-binding protein involved in various cellular processes such as centrosome duplication and DNA repair. Raised in rabbits, this antibody exhibits high specificity and reactivity with human samples, making it suitable for use in Western blot and immunofluorescence applications. Centrin-1 is a key player in maintaining cellular structure and function, particularly in the context of cell division and genome stability.
Dysregulation of Centrin-1 has been linked to abnormal cell growth and potential implications in diseases such as cancer. By utilizing the Centrin-1 Polyclonal Antibody, researchers can accurately detect and analyze Centrin-1 expression levels in different cell types, providing valuable insights into its role in biological processes and disease pathogenesis.
Product Name:
CETN1 Rabbit Polyclonal Antibody
SKU:
CAB3784
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CETN1 (NP_004057.1).
The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.
Purification Method:
Affinity purification
Gene ID:
1068
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CETN1 antibody (CAB3784) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
