The CERS5 Polyclonal Antibody (CAB17240) is a valuable tool for researchers studying the CERS5 protein, which is involved in ceramide synthesis and regulation of sphingolipid metabolism. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the CERS5 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in lipid metabolism and related diseases such as cancer and metabolic disorders.
Understanding the function of CERS5 is crucial for unraveling its role in cellular processes and developing targeted therapies for diseases associated with sphingolipid dysregulation.
Product Name:
CERS5 Rabbit Polyclonal Antibody
SKU:
CAB17240
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CERS5 (NP_001268660.1).
This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
91012
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells, using CERS5 Rabbit pAb (CAB17240) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
