The CERS5 Polyclonal Antibody (CAB17239) is a valuable tool for studying the CERS5 protein, which plays a crucial role in ceramide synthesis and regulation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the CERS5 protein, researchers can investigate its role in lipid metabolism, cell signaling, and cellular stress response pathways.CERS5, also known as ceramide synthase 5, is a key enzyme in the biosynthesis of ceramides, important lipid molecules that are involved in various cellular processes such as apoptosis, cell proliferation, and inflammation.
Dysregulation of ceramide levels has been linked to several diseases, including cancer, neurodegenerative disorders, and metabolic disorders. Studying the function of CERS5 can provide important insights into these pathological conditions and potential targets for therapeutic interventions.Overall, the CERS5 Polyclonal Antibody (CAB17239) is a valuable tool for researchers interested in elucidating the role of ceramide metabolism in health and disease. Its specificity and reliability make it an essential component of studies focusing on lipid biology, cell signaling, and therapeutic development.
Product Name:
CERS5 Rabbit Polyclonal Antibody
SKU:
CAB17239
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CERS5 (NP_001268660.1).
This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
91012
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CERS5 Rabbit pAb (CAB17239) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
