CERKL Rabbit Polyclonal Antibody (CAB15984)
- SKU:
- CAB15984
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CERKL Rabbit Polyclonal Antibody |
SKU: | CAB15984 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 359-558 of human CERKL (NP_001025482.1). |
Sequence: | LAEK YRWM SPNQ RRDF AVVK ALAK LKAE DCEI SFLP FNSS DDVQ ERRA QGSP KSDC NDQW QMIQ GQFL NVSI MAIP CLCS VAPR GLAP NTRL NNGS MALI IARN TSRP EFIK HLKR YASV KNQF NFPF VETY TVEE VKVH PRNN TGGY NPEE EEDE TASE NCFP WNVD GDLM EVAS EVHI RLHP RLIS LYGG SMEE MIPK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RP26; CERKL |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Nucleus, nucleolus, nucleolus, trans-Golgi network. |
Calculated MW: | 63kDa |
Observed MW: | 63kDa |
This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.
Purification Method: | Affinity purification |
Gene ID: | 375298 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |