UniProt Protein Function: | CEPT1: Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity. Belongs to the CDP-alcohol phosphatidyltransferase class-I family.Protein type: EC 2.7.8.1; Membrane protein, integral; EC 2.7.8.2; Endoplasmic reticulum; Transferase; Membrane protein, multi-passChromosomal Location of Human Ortholog: 1p13.3Cellular Component: endoplasmic reticulum membrane; nuclear membrane; integral to membraneMolecular Function: diacylglycerol cholinephosphotransferase activity; ethanolaminephosphotransferase activity; metal ion bindingBiological Process: CDP-choline pathway; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylcholine biosynthetic process; lipid metabolic process |
UniProt Protein Details: | |
NCBI Summary: | Cholinephosphotransferase catalyses the final step in the synthesis of phosphatidylcholine by the transfer of phosphocholine from CDP-choline to diacylglycerol. The synthesis of phosphatidylethanolamine by ethanolaminephosphotransferase occurs using an analogous reaction. This gene codes for a choline/ethanolaminephosphotransferase. The protein can synthesize either choline- or ethanolamine- containing phospholipids. Two alternatively spliced transcripts encoding the same isoform have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y6K0 |
NCBI GenInfo Identifier: | 56118223 |
NCBI Gene ID: | 10390 |
NCBI Accession: | NP_001007795.1 |
UniProt Secondary Accession: | Q9Y6K0,Q69YJ9, Q9P0Y8 |
UniProt Related Accession: | Q9Y6K0 |
Molecular Weight: | |
NCBI Full Name: | choline/ethanolaminephosphotransferase 1 |
NCBI Synonym Full Names: | choline/ethanolamine phosphotransferase 1 |
NCBI Official Symbol: | CEPT1Â Â |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | choline/ethanolaminephosphotransferase 1 |
UniProt Protein Name: | Choline/ethanolaminephosphotransferase 1 |
UniProt Synonym Protein Names: | |
Protein Family: | Choline/ethanolaminephosphotransferase |
UniProt Gene Name: | CEPT1Â Â |
UniProt Entry Name: | CEPT1_HUMAN |