The CEPT1 Polyclonal Antibody (PACO08371) is a valuable tool for researchers studying the CEPT1 protein, which is involved in lipid metabolism and cellular homeostasis. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.CEPT1, also known as choline/ethanolamine phosphotransferase 1, plays a crucial role in the synthesis of phosphatidylcholine, a major component of cell membranes. Dysregulation of CEPT1 has been linked to various diseases, including cancer and metabolic disorders.
By targeting CEPT1 with this antibody, researchers can better understand its function and potential as a therapeutic target in these conditions.With its high reactivity and specificity, the CEPT1 Polyclonal Antibody is an essential tool for studies in lipid metabolism, cell biology, and disease research. Its ability to detect and analyze CEPT1 protein expression in various cell types makes it an ideal choice for scientists working in these fields.
CEPT1: Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity. Belongs to the CDP-alcohol phosphatidyltransferase class-I family.Protein type: EC 2.7.8.1; Membrane protein, integral; EC 2.7.8.2; Endoplasmic reticulum; Transferase; Membrane protein, multi-passChromosomal Location of Human Ortholog: 1p13.3Cellular Component: endoplasmic reticulum membrane; nuclear membrane; integral to membraneMolecular Function: diacylglycerol cholinephosphotransferase activity; ethanolaminephosphotransferase activity; metal ion bindingBiological Process: CDP-choline pathway; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylcholine biosynthetic process; lipid metabolic process
UniProt Protein Details:
NCBI Summary:
Cholinephosphotransferase catalyses the final step in the synthesis of phosphatidylcholine by the transfer of phosphocholine from CDP-choline to diacylglycerol. The synthesis of phosphatidylethanolamine by ethanolaminephosphotransferase occurs using an analogous reaction. This gene codes for a choline/ethanolaminephosphotransferase. The protein can synthesize either choline- or ethanolamine- containing phospholipids. Two alternatively spliced transcripts encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]
