The CEP97 Antibody (PACO5366) is a polyclonal antibody specifically designed for research involving CEP97, a protein involved in centrosome duplication and cell cycle progression. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications including immunofluorescence and immunohistochemistry.CEP97 is a critical component of the centrosome, a crucial organelle involved in cell division and organization. Dysregulation of centrosome duplication can lead to chromosomal instability and cell cycle defects, which are hallmarks of cancer development.
Understanding the role of CEP97 in these processes is essential for unraveling the mechanisms underlying cancer progression and identifying potential therapeutic targets.By using the CEP97 Antibody, researchers can effectively detect and analyze CEP97 expression in different cell types and tissues, providing valuable insights into its function and potential implications in disease. This antibody is a valuable tool for studies in cell biology, cancer research, and developmental biology, offering researchers the opportunity to uncover new avenues for therapeutic intervention.
Antibody Name:
CEP97 Antibody (PACO05366)
Antibody SKU:
PACO05366
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from the Internal region of human Cep97.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
CEP97; LRRIQ2; Centrosomal protein of 97 kDa; Cep97; Leucine-rich repeat and IQ domain-containing protein 2
UniProt Protein Function:
LRRIQ2: Collaborates with CCP110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of CCP110 to the centrosome. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3q12.3Cellular Component: centrosome; protein complex; cytoplasm; microtubule organizing center; cytosolMolecular Function: calmodulin binding; protein bindingBiological Process: cell projection organization and biogenesis; organelle organization and biogenesis
