The CEP89 Polyclonal Antibody (PAC050918) is a key tool for researchers studying the function of CEP89, a centrosomal protein involved in cell division and ciliogenesis. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blotting. By targeting the CEP89 protein, this antibody enables precise detection and analysis in various cell types, making it well-suited for studies in cell biology and developmental biology.CEP89 is essential for centrosome function and plays a crucial role in organizing microtubules during cell division. Additionally, it is involved in the formation and maintenance of cilia, cellular structures that are important for a variety of physiological processes.
Research on CEP89 is instrumental in understanding the mechanisms underlying cell division, cilia formation, and related diseases such as ciliopathies and cancer.The CEP89 Polyclonal Antibody offers researchers a reliable tool for investigating the function and regulation of CEP89 in cells, providing insights into fundamental biological processes and potential therapeutic targets for various diseases. Its high specificity and reactivity make it a valuable asset for studies aimed at unraveling the complexities of cell biology and exploring novel therapeutic strategies.
Antibody Name:
CEP89 Antibody (PACO50918)
Antibody SKU:
PACO50918
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Centrosomal protein of 89 kDa protein (25-235AA)
Required for ciliogenesis. Also plays a role in mitochondrial metabolism where it may modulate complex IV activity.
Synonyms:
Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123), CEP89, CCDC123
UniProt Protein Function:
CCDC123: 3 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 19q13.11Cellular Component: centriole; spindle pole; centrosome; cytoplasm; plasma membrane; mitochondrial intermembrane space; cytosolBiological Process: organelle organization and biogenesis; cilium biogenesis
