The CEP85 Polyclonal Antibody (CAB15891) is a valuable tool for researchers studying the protein CEP85, a centrosome-associated protein involved in cell division and ciliogenesis. This antibody, developed using rabbit immunization, is highly specific for human samples and has been rigorously validated for use in Western blot applications. By specifically binding to the CEP85 protein, this antibody allows for accurate detection and analysis of CEP85 expression in various cell types, making it an essential tool for studies in cell biology and developmental biology.
CEP85 plays a crucial role in centrosome function and centriole duplication, making it a key player in the regulation of cell division and cilia formation. Dysregulation of CEP85 has been implicated in various diseases, including ciliopathies and cancer, making it an attractive target for therapeutic intervention. Research using the CEP85 Polyclonal Antibody can help shed light on the molecular mechanisms underlying these diseases and pave the way for the development of novel treatments targeting CEP85.
Product Name:
CEP85 Rabbit Polyclonal Antibody
SKU:
CAB15891
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-430 of human CEP85 (NP_073615.2).
Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center, nucleolus, spindle pole.
Calculated MW:
86kDa
Observed MW:
105kDa
This gene encodes a protein that belongs to the centrosome-associated family of proteins. The centrosome is a subcellular organelle in the animal cell that functions as a microtubule organizing center and is involved in cell-cycle progression. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
64793
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CEP85 Rabbit pAb (CAB15891) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.