The CEP63 Polyclonal Antibody (CAB15516) is a valuable tool for researchers studying the centrosomal protein CEP63, known for its role in regulating centriole duplication and cell cycle progression. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting CEP63 in human samples, making it suitable for use in various experimental applications such as Western blotting.CEP63 is a key player in centrosome biology, essential for proper cell division and genome stability.
Dysfunction in CEP63 has been associated with diseases like microcephaly and ciliopathy, highlighting its importance in cellular processes. By utilizing the CEP63 Polyclonal Antibody, researchers can delve deeper into the functions and mechanisms of CEP63, leading to insights that could potentially impact studies on developmental disorders and cancer biology.
Product Name:
CEP63 Rabbit Polyclonal Antibody
SKU:
CAB15516
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CEP63 (NP_001035859.1).
This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
80254
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CEP63 Rabbit pAb (CAB15516) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
