The CEP44 Polyclonal Antibody (CAB8317) is a valuable tool for researchers studying CEP44, a centrosomal protein involved in cell division and ciliogenesis. This antibody is produced in rabbits and specifically targets the CEP44 protein in human samples, making it ideal for use in Western blotting applications. By detecting and analyzing CEP44 expression in various cell types, this antibody aids in the exploration of its role in cellular processes and its potential implications in diseases such as cancer and ciliopathy disorders.CEP44 is known for its essential function in centrosome biology, playing a key role in maintaining genome stability and regulating microtubule organization during cell division.
Dysregulation of CEP44 has been associated with abnormal cell proliferation and ciliogenesis defects, highlighting its importance in cellular homeostasis. Research on CEP44 opens up new avenues for understanding the molecular mechanisms underlying diseases linked to centrosome dysfunction and provides insights for developing targeted therapies in the future.
Product Name:
CEP44 Rabbit Polyclonal Antibody
SKU:
CAB8317
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human CEP44 (NP_001035247.1).
Cytoplasm, Midbody, centrosome, cytoskeleton, microtubule organizing center, spindle pole.
Calculated MW:
44kDa
Observed MW:
45kDa
Enables microtubule binding activity. Involved in centriole replication and centriole-centriole cohesion. Located in centriole; centrosome; and spindle pole.
Purification Method:
Affinity purification
Gene ID:
80817
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CEP44 antibody (CAB8317) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
