CEP290 Rabbit Polyclonal Antibody (CAB16147)
- SKU:
- CAB16147
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CEP290 Rabbit Polyclonal Antibody |
SKU: | CAB16147 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 950-1050 of human CEP290 (NP_079390.3). |
Sequence: | QKVV DNSV SLSE LELA NKQY NELT AKYR DILQ KDNM LVQR TSNL EHLE CENI SLKE QVES INKE LEIT KEKL HTIE QAWE QETK LGNE SSMD KAKK SITN S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CT87; MKS4; POC3; rd16; BBS14; JBTS5; LCA10; NPHP6; SLSN6; 3H11Ag; CEP290 |
Positive Sample: | U-87MG,DU145 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Nucleus, centriolar satellite, centriole, centrosome, cilium, cilium basal body, cytoskeleton, microtubule organizing center |
Calculated MW: | 290kDa |
Observed MW: | 290kDa |
This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.
Purification Method: | Affinity purification |
Gene ID: | 80184 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |