CEP126 Antibody (PACO40934)
- SKU:
- PACO40934
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
CEP126 Antibody (PACO40934)
The CEP126 Polyclonal Antibody (PAC040934) is a powerful tool for researchers studying the CEP126 protein, a key player in centriole biogenesis and ciliogenesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been extensively validated for use in Western blot applications. By binding specifically to CEP126, it allows for accurate detection and analysis of this important protein in a variety of cell types, making it an invaluable resource for studies in cell biology and developmental biology.
CEP126 is involved in the formation of centrioles, essential structures involved in cell division and cilia assembly. Dysfunction of CEP126 has been linked to abnormalities in centriole duplication and ciliogenesis, which can lead to a range of developmental defects and diseases. By studying the function of CEP126, researchers can gain insights into the mechanisms underlying these conditions, potentially leading to the development of novel therapeutic strategies.
| Antibody Name: | CEP126 Antibody (PACO40934) |
| Antibody SKU: | PACO40934 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Centrosomal protein of 126 kDa protein (559-670AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO40934 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO40934 at dilution of 1:100. |
| Background: | May participate in cytokinesis. |
| Synonyms: | Centrosomal protein of 126 kDa, CEP126, KIAA1377 |
| UniProt Protein Function: | CEP126: May participate in cytokinesis |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 11q22.1 Cellular Component: centrosome; midbody Molecular Function:protein binding Biological Process: cytoplasmic microtubule organization and biogenesis; mitotic spindle organization and biogenesis |
| UniProt Code: | Q9P2H0 |
| NCBI GenInfo Identifier: | 612149776 |
| NCBI Gene ID: | 57562 |
| NCBI Accession: | NP_065853.3 |
| UniProt Secondary Accession: | Q9P2H0,Q4G0U6, |
| UniProt Related Accession: | Q9P2H0 |
| Molecular Weight: | 28.9kD |
| NCBI Full Name: | centrosomal protein of 126 kDa |
| NCBI Synonym Full Names: | centrosomal protein 126 |
| NCBI Official Symbol: | CEP126Â Â |
| NCBI Official Synonym Symbols: | KIAA1377Â Â |
| NCBI Protein Information: | centrosomal protein of 126 kDa |
| UniProt Protein Name: | Centrosomal protein of 126 kDa |
| UniProt Gene Name: | CEP126Â Â |
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