The CEP120 Polyclonal Antibody (CAB8004) is a valuable tool for researchers studying the CEP120 protein, which plays a crucial role in centriole duplication and cell division. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to CEP120, this antibody allows for accurate detection and analysis of the protein in various cell types, making it an essential tool for studies in cell biology and cancer research.CEP120 is a key player in centriole formation and duplication, processes that are essential for accurate cell division and genome stability.
Dysregulation of CEP120 has been linked to various human diseases, including cancer and genetic disorders. By investigating the function of CEP120 with the help of this antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets. Understanding the role of CEP120 paves the way for the development of novel treatments aimed at correcting abnormalities in cell division and preventing disease progression.
Product Name:
CEP120 Rabbit Polyclonal Antibody
SKU:
CAB8004
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CEP120 (NP_694955.2).
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
153241
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CEP120 antibody (CAB8004) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
