The CEP112 Polyclonal Antibody (CAB14302) is a valuable tool for researchers studying CEP112, a cell cycle regulatory protein involved in cell division and DNA damage response. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CEP112 protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it ideal for studies in cell biology, cancer research, and drug development.
CEP112 plays a crucial role in maintaining genomic stability and proper cell division, making it a key target for understanding the mechanisms underlying cancer development and progression. By studying CEP112, researchers can gain insight into how disruptions in cell cycle regulation contribute to cancer and potentially identify new therapeutic targets for treatment. The CEP112 Polyclonal Antibody is a reliable tool for investigating the functions of CEP112 and its implications for cancer biology.
Product Name:
CEP112 Rabbit Polyclonal Antibody
SKU:
CAB14302
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CEP112 (NP_659473.2).
This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
201134
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CEP112 Rabbit pAb (CAB14302) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
