The Centrin-2 Polyclonal Antibody (CAB5397) is a valuable tool for researchers studying Centrin-2, a calcium-binding protein involved in various cellular processes such as centriole duplication and DNA repair. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications.Centrin-2 is a key player in centriole biology, where it plays a crucial role in maintaining centriole structure and function. Dysregulation of centriole duplication has been implicated in various diseases, including cancer and ciliopathies. By using the Centrin-2 Polyclonal Antibody, researchers can detect and analyze Centrin-2 protein expression in different cell types, providing insights into its role in cellular processes and disease mechanisms.
This antibody is an essential tool for studies in cell biology, cancer research, and developmental biology, where understanding the functions of Centrin-2 is essential for elucidating its contribution to cellular physiology and disease pathogenesis. By targeting Centrin-2, researchers can gain valuable insights that may lead to the development of novel therapeutic strategies for diseases associated with centriole dysfunction.
Product Name:
[KO Validated] CETN2 Rabbit Polyclonal Antibody
SKU:
CAB5397
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CETN2 (NP_004335.1).
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome.
Purification Method:
Affinity purification
Gene ID:
1069
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CETN2 antibody (CAB5397) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
