The CENPN Rabbit Polyclonal Antibody (CAB17731) is a valuable tool for research involving CENPN, a protein involved in cell division processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CENPN protein, this antibody allows for the detection and analysis of CENPN expression in various cell types, making it ideal for studies in cell biology and oncology research.CENPN, also known as centromere protein N, plays a crucial role in ensuring the accurate segregation of chromosomes during cell division.
Dysregulation of CENPN has been associated with chromosomal instability and cancer progression, highlighting its importance in cellular processes. Research into the function of CENPN is essential for understanding its role in cancer development and identifying potential therapeutic targets for cancer treatment.Overall, the CENPN Rabbit Polyclonal Antibody (CAB17731) is a reliable tool for researchers studying cell division and cancer biology, providing valuable insights into the functions of CENPN and its implications in disease progression.
Product Name:
CENPN Rabbit Polyclonal Antibody
SKU:
CAB17731
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human CENPN (NP_001094094).
The protein encoded by this gene forms part of the nucleosome-associated complex and is important for kinetochore assembly. It is bound to kinetochores during S phase and G2 and recruits other proteins to the centromere. Pseudogenes of this gene are located on chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method:
Affinity purification
Gene ID:
55839
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CENPN Rabbit pAb (CAB17731) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
