The CENPK Polyclonal Antibody (CAB7627) is a valuable tool for researchers studying the CENPK protein, which is involved in cell division and chromosome segregation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By binding specifically to the CENPK protein, this antibody allows for the detection and analysis of CENPK in various cell types, making it an essential component for studies in cell biology and cancer research.CENPK, also known as centromere protein K, is a key player in ensuring the proper distribution of chromosomes during cell division.
Dysregulation of CENPK has been implicated in cancer development and progression, making it a promising target for therapeutic interventions. By understanding the function and regulation of CENPK, researchers can gain insight into the mechanisms underlying cancer and potentially develop novel treatment strategies targeted at this protein.Overall, the CENPK Polyclonal Antibody (CAB7627) is a powerful tool for scientists investigating the role of CENPK in cellular processes and disease progression, offering reliable and specific detection of this important protein in research settings.
Product Name:
CENPK Rabbit Polyclonal Antibody
SKU:
CAB7627
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human CENPK (NP_071428.2).
CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).
Purification Method:
Affinity purification
Gene ID:
64105
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CENPK Antibody (CAB7627) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
