CENPJ Rabbit Polyclonal Antibody (CAB8721)
- SKU:
- CAB8721
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CENPJ Rabbit Polyclonal Antibody |
SKU: | CAB8721 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1069-1338 of human CENPJ (NP_060921.3). |
Sequence: | DKLA NTSV RFQN SQIS SGTQ VEKY KKNY LPMQ GNPP RRSK SAPP RDLG NLDK GQAA SPRE PLEP LNFP DPEY KEEE EDQD IQGE ISHP DGKV EKVY KNGC RVIL FPNG TRKE VSAD GKTI TVTF FNGD VKQV MPDQ RVIY YYAA AQTT HTTY PEGL EVLH FSSG QIEK HYPD GRKE ITFP DQTV KNLF PDGQ EESI FPDG TIVR VQRD GNKL IEFN NGQR ELHT AQFK RREY PDGT VKTV YANG HQET KYRS GRIR VKDK EGNV LMDT EL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LAP; CPAP; LIP1; BM032; MCPH6; SASS4; SCKL4; Sas-4; CENP-J; CENPJ |
Positive Sample: | Raji |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centriole, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 153kDa |
Observed MW: | 153kDa |
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 55835 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |