CENPF Rabbit Polyclonal Antibody (CAB18644)
- SKU:
- CAB18644
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CENPF Rabbit Polyclonal Antibody |
SKU: | CAB18644 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1730-1890 of human CENPF (NP_057427.3). |
Sequence: | NYEP PGED KTQG SSEC ISEL SFSG PNAL VPMD FLGN QEDI HNLQ LRVK ETSN ENLR LLHV IEDR DRKV ESLL NEMK ELDS KLHL QEVQ LMTK IEAC IELE KIVG ELKK ENSD LSEK LEYF SCDH QELL QRVE TSEG LNSD LEMH ADKS SRED IGDN VAKV N |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CENF; hcp-1; CILD31; STROMS; PRO1779; CENPF |
Positive Sample: | HeLa |
Cellular Localization: | axoneme, centrosome, ciliary basal body, ciliary transition fiber, cytoplasm, cytosol, nuclear envelope, nuclear matrix, nucleoplasm, nucleus, perinuclear region of cytoplasm, pronucleus, spindle, spindle pole |
Calculated MW: | 358kDa |
Observed MW: | 330kDa |
This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.
Purification Method: | Affinity purification |
Gene ID: | 1063 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |