CENPA Rabbit Polyclonal Antibody (CAB15995)
- SKU:
- CAB15995
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CENPA Rabbit Polyclonal Antibody |
SKU: | CAB15995 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CENPA (NP_001800.1). |
Sequence: | MGPR RRSR KPEA PRRR SPSP TPTP GPSR RGPS LGAS SHQH SRRR QGWL KEIR KLQK STHL LIRK LPFS RLAR EICV KFTR GVDF NWQA QALL ALQE AAEA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CenH3; CENP-A; CENPA |
Positive Sample: | HCT116,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, nucleoplasm, nucleus |
Calculated MW: | 16kDa |
Observed MW: | 18kDa |
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 1058 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |