CELSR1 Polyclonal Antibody
- SKU:
- CAB20779
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | CELSR1 Polyclonal Antibody |
Product Code: | CAB20779 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Cellular Location: | nucleoplasm, plasma membrane |
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CELSR1 (NP_055061.1). |
Sequence: | YAVGA ACTPR APREL LDVGR DGRLA GRRRV SGAGR PLPLQ VRLVA RSAPT ALSRR LRART HLPGC GARAR LCGTG ARLCG ALCFP VPGGC AAAQH SALAA P |
Synonyms: | ME2, FMI2, CDHF9, HFMI2, ADGRC1, LMPHM9 |
Calculated MW: | 329kDa |
Observed MW: | Refer to figures |