The Cellubrevin Rabbit Monoclonal Antibody (CAB8812) is a highly specific antibody designed for research involving Cellubrevin, a protein involved in intracellular membrane fusion events. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot and immunofluorescence applications.Cellubrevin is a key player in vesicle trafficking and neurotransmitter release, making it of interest in studies of synaptic transmission, neurobiology, and neurodegenerative diseases. The Cellubrevin Rabbit Monoclonal Antibody enables accurate detection and analysis of this protein in various cell types, providing valuable insights into its function and importance in cellular processes.
With its high specificity and sensitivity, the Cellubrevin Rabbit Monoclonal Antibody is a valuable tool for researchers studying membrane fusion events, synaptic function, and neurological disorders. Its use in immunofluorescence allows for visualization of Cellubrevin localization within cells, further enhancing the understanding of its role in intracellular trafficking pathways.
Product Name:
VAMP3/Cellubrevin Rabbit Monoclonal Antibody
SKU:
CAB8812
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human VAMP3/Cellubrevin (Q15836).
Cell junction, Membrane, Single-pass type IV membrane protein, synapse, synaptosome.
Calculated MW:
11kDa
Observed MW:
15kDa
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
Purification Method:
Affinity purification
Gene ID:
9341
Clone Number:
ARC1312
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using VAMP3/VAMP3/Cellubrevin Rabbit mAb (CAB8812) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
