The CELF5 Polyclonal Antibody (CAB18482) is a valuable tool for researchers studying CELF5, a key RNA-binding protein involved in RNA processing and regulation. This rabbit polyclonal antibody is highly specific and reacts strongly with human samples, making it ideal for applications such as Western blotting. By binding to the CELF5 protein, this antibody enables the detection and analysis of CELF5 in various cell types, providing insights into its role in gene expression regulation.CELF5 is known to play a crucial role in post-transcriptional control of gene expression, particularly in the nervous system.
Dysregulation of CELF5 has been linked to neurodevelopmental disorders and neurological diseases, making it a promising target for further research. Understanding the function of CELF5 can provide valuable insights into RNA metabolism and its implications for health and disease. Researchers studying gene expression, RNA processing, and neurobiology can benefit from the use of the CELF5 Polyclonal Antibody in their investigations.
Product Name:
CELF5 Rabbit Polyclonal Antibody
SKU:
CAB18482
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-45 of human CELF5 (NP_001166144.1).
This gene encodes a member of the the CELF/BRUNOL protein family, which contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing and translation. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
60680
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CELF5 Rabbit pAb (CAB18482) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
