CELF1 Rabbit Polyclonal Antibody (CAB5958)
- SKU:
- CAB5958
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | CELF1 Rabbit Polyclonal Antibody |
SKU: | CAB5958 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 108-483 of human CELF1 (NP_941989.1). |
Sequence: | RKLF IGMI SKKC TEND IRVM FSSF GQIE ECRI LRGP DGLS RGCA FVTF TTRA MAQT AIKA MHQA QTME GCSS PMVV KFAD TQKD KEQK RMAQ QLQQ QMQQ ISAA SVWG NLAG LNTL GPQY LALL QQTA SSGN LNTL SSLH PMGG LNAM QLQN LAAL AAAA SAAQ NTPS GTNA LTTS SSPL SVLT SSAG SSPS SSSS NSVN PIAS LGAL QTLA GATA GLNV GSLA GMAA LNGG LGSS GLSN GTGS TMEA LTQA YSGI QQYA AAAL PTLY NQNL LTQQ SIGA AGSQ KEGP EGAN LFIY HLPQ EFGD QDLL QMFM PFGN VVSA KVFI DKQT NLSK CFGF VSYD NPVS AQAA IQSM NGFQ IGMK RLKV QLKR SKND SKPY |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | CUGBP; NAB50; NAPOR; CUG-BP; CUGBP1; hNab50; BRUNOL2; EDEN-BP; CELF1 |
Positive Sample: | U-87MG,SH-SY5Y,HepG2,NIH/3T3,HeLa,Mouse liver,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 10658 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |