The CEL Polyclonal Antibody (CAB7652) is a valuable tool for researchers studying CEL, a key protein involved in various cellular processes. This antibody, derived from rabbit hosts, exhibits strong reactivity towards CEL in human samples, making it a reliable option for Western blot experiments. By specifically binding to the CEL protein, researchers can accurately detect and analyze its expression in different cell types, enabling a deeper understanding of its role in various biological pathways.CEL, also known as carboxyl ester lipase, plays a vital role in lipid metabolism and digestion, making it an attractive target for studies in metabolic disorders, gastrointestinal diseases, and obesity-related conditions.
By investigating the functions of CEL, researchers can uncover potential therapeutic targets for these health issues, paving the way for the development of innovative treatment strategies.In conclusion, the CEL Polyclonal Antibody (CAB7652) offers researchers a reliable tool for investigating the functions and significance of CEL in various physiological processes. Its high reactivity and specificity make it a valuable asset for studies in biochemistry, molecular biology, and medical research.
Product Name:
CEL Rabbit Polyclonal Antibody
SKU:
CAB7652
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-550 of human CEL (NP_001798.2).
BAL; FAP; BSDL; BSSL; CELL; FAPP; LIPA; CEase; MODY8; CEL
Positive Sample:
Raji,Mouse spleen
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
79kDa
Observed MW:
71kDa
The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.
Purification Method:
Affinity purification
Gene ID:
1056
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CEL antibody (CAB7652) at 1:500 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 30s.
