The CEBPZ Polyclonal Antibody (CAB16478) is a crucial tool for researchers studying the CEBPZ protein, a transcription factor involved in regulating gene expression and cellular processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the CEBPZ protein, researchers can accurately detect and analyze its expression in various cell types, making it an ideal choice for studies in molecular biology and cancer research.
CEBPZ is known for its role in modulating gene expression and influencing cellular functions such as proliferation, differentiation, and apoptosis. Understanding the intricate mechanisms of CEBPZ can provide valuable insights into the development and progression of diseases, particularly cancer and inflammatory disorders. By investigating the functions and regulatory pathways of CEBPZ, researchers can uncover potential therapeutic targets and strategies for treating these conditions.
Product Name:
CEBPZ Rabbit Polyclonal Antibody
SKU:
CAB16478
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CEBPZ (NP_005751.2).
This gene belongs to the CBF/Mak21 family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation.
Purification Method:
Affinity purification
Gene ID:
10153
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CEBPZ Rabbit pAb (CAB16478) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
