The CEBPE Polyclonal Antibody (CAB8047) is a valuable tool for researchers studying CEBPE, a transcription factor known to play a crucial role in regulating gene expression in immune cells. This antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications.CEBPE is involved in the differentiation and function of various immune cell types, including granulocytes and dendritic cells. By targeting the CEBPE protein, this antibody allows for the detection and analysis of CEBPE expression in a variety of cell types, making it an essential tool for immunology and cancer research studies.
The importance of CEBPE in immune cell development and function highlights its relevance in various disease contexts, such as cancer and inflammatory disorders. By investigating the role of CEBPE using this antibody, researchers can gain valuable insights into the molecular mechanisms underlying immune responses and potentially develop targeted therapies for related diseases.
Product Name:
CEBPE Rabbit Polyclonal Antibody
SKU:
CAB8047
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CEBPE (NP_001796.2).
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined.
Purification Method:
Affinity purification
Gene ID:
1053
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CEBPE antibody (CAB8047) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
