CEBPD/CEBPE Antibody (PACO06937)
- SKU:
- PACO06937
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
CEBPD/CEBPE Antibody (PACO06937)
The CEBPD/CEBPE Antibody (PAC06937) is a high-quality polyclonal antibody designed for research involving CEBPD and CEBPE proteins, key transcription factors involved in gene regulation and cell differentiation. This antibody, produced in rabbits, is specifically reactive with human samples and has been validated for use in various applications, including Western blotting.CEBPD and CEBPE are important regulators of cellular processes, such as growth, differentiation, and immune responses. The antibody binds to these proteins, allowing for their detection and analysis in a variety of cell types.
This makes it a valuable tool for researchers studying gene regulation, immune response modulation, and cancer biology.The CEBPD/CEBPE Antibody is essential for investigations into the role of these transcription factors in diseases like cancer, inflammation, and immune disorders. Understanding their function and regulation is crucial for developing targeted therapies and diagnostic tools for these conditions. Trust this antibody to provide reliable and accurate results in your research endeavors.
| Antibody Name: | CEBPD/CEBPE Antibody (PACO06937) |
| Antibody SKU: | PACO06937 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human C/EBP delta / epsilon . |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of RAT-MUSCLE cells using C/EBP delta / epsilon Polyclonal Antibody. |
 | Western Blot analysis of LOVO cells using C/EBP delta / epsilon Polyclonal Antibody. |
| Synonyms: | CEBPD; CCAAT/enhancer-binding protein delta; C/EBP delta; Nuclear factor NF-IL6-β; NF-IL6-β; CEBPE; CCAAT/enhancer-binding protein epsilon; C/EBP epsilon |
| UniProt Protein Function: | C/EBP-delta: C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha. Interacts with SPI1/PU.1. Interacts with PRDM16. Belongs to the bZIP family. C/EBP subfamily. |
| UniProt Protein Details: | Protein type:DNA-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 8p11.2-p11.1 Cellular Component: nucleus Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010] |
| UniProt Code: | P49716 |
| NCBI GenInfo Identifier: | 160332350 |
| NCBI Gene ID: | 1052 |
| NCBI Accession: | P49716.2 |
| UniProt Secondary Accession: | P49716,Q03484, |
| UniProt Related Accession: | P49716 |
| Molecular Weight: | 269 |
| NCBI Full Name: | CCAAT/enhancer-binding protein delta |
| NCBI Synonym Full Names: | CCAAT/enhancer binding protein (C/EBP), delta |
| NCBI Official Symbol: | CEBPDÂ Â |
| NCBI Official Synonym Symbols: | CELF; CRP3; C/EBP-delta; NF-IL6-beta  |
| NCBI Protein Information: | CCAAT/enhancer-binding protein delta; c/EBP delta; nuclear factor NF-IL6-beta |
| UniProt Protein Name: | CCAAT/enhancer-binding protein delta |
| UniProt Synonym Protein Names: | Nuclear factor NF-IL6-beta; NF-IL6-beta |
| Protein Family: | CCAAT/enhancer-binding protein |
| UniProt Gene Name: | CEBPDÂ Â |
| UniProt Entry Name: | CEBPD_HUMAN |
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