CEBPA Rabbit Polyclonal Antibody (CAB0904)
- SKU:
- CAB0904
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | CEBPA Rabbit Polyclonal Antibody |
SKU: | CAB0904 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-180 of human CEBPA (NP_004355.2). |
Sequence: | APAG PGGA VMPG GAHG PPPG YGCA AAGY LDGR LEPL YERV GAPA LRPL VIKQ EPRE EDEA KQLA LAGL FP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | CEBP; C/EBP-alpha; CEBPA |
Positive Sample: | LO2,Mouse kidney,Rat lung,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Nucleus, nucleolus. |
Calculated MW: | 38kDa |
Observed MW: | 30kDa/42kDa |
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.
Purification Method: | Affinity purification |
Gene ID: | 1050 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |