The CEACAM6 Polyclonal Antibody (CAB8440) is a valuable tool for researchers studying CEACAM6, a cell surface glycoprotein associated with immune function and tumorigenesis. Raised in rabbits, this antibody exhibits high reactivity with human samples and is validated for use in applications such as Western blotting. By specifically binding to the CEACAM6 protein, researchers can easily detect and analyze its expression in various cell types, making it well-suited for studies in immunology and cancer research.
CEACAM6, also known as Carcinoembryonic Antigen-related Cell Adhesion Molecule 6, plays a crucial role in immune response modulation and has been implicated in the development and progression of various cancers. Understanding the function of CEACAM6 is essential for advancing research in cancer biology and immunotherapy. By targeting CEACAM6, researchers may uncover new therapeutic strategies for treating cancer and other related diseases.
Product Name:
CEACAM6 Rabbit Polyclonal Antibody
SKU:
CAB8440
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-320 of human CEACAM6 (NP_002474.4).
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
Purification Method:
Affinity purification
Gene ID:
4680
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of A-549, using CEACAM6 Rabbit pAb (CAB8440) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
