The CEACAM6 Monoclonal Antibody is a valuable tool for researchers studying CEACAM6, a cell surface glycoprotein that is overexpressed in various cancers, including colon, lung, and breast cancer. This monoclonal antibody, developed for use in laboratory research, is highly specific and validated for applications such as immunohistochemistry and flow cytometry.CEACAM6, also known as CD66c, is involved in cell adhesion and signaling processes, making it a potential target for cancer therapy and diagnosis.
By using this antibody, researchers can study the expression and function of CEACAM6 in cancer cells, providing insights into tumor progression and potential therapeutic strategies.With its high specificity and versatility in various experimental techniques, the CEACAM6 Monoclonal Antibody is a valuable tool for advancing research in cancer biology and personalized medicine, ultimately contributing to the development of new diagnostic and treatment approaches for cancer patients.
Product Name:
CEACAM6 Monoclonal Antibody
SKU:
CAB22671
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-320 of human CEACAM6 (NP_002474.4).
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
Purification Method:
Affinity purification
Gene ID:
4680
Clone Number:
ARC54333
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various lysates, using CEACAM6 antibody (CAB22671) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
