The CEACAM5 Polyclonal Antibody (CAB12421) is specifically designed for researchers studying CEACAM5, a cell surface glycoprotein that is involved in cell adhesion and signaling pathways. This antibody is raised in rabbits and has been validated for use in Western blot applications, allowing for the detection and analysis of CEACAM5 protein in human samples.CEACAM5, also known as carcinoembryonic antigen-related cell adhesion molecule 5, is a member of the CEA family and is commonly overexpressed in various types of cancer, making it a potential biomarker for cancer diagnosis and prognosis.
By targeting CEACAM5 with this polyclonal antibody, researchers can further study its role in cancer progression and potentially develop new therapeutic strategies for cancer treatment.With its high reactivity and specificity for human samples, the CEACAM5 Polyclonal Antibody is a valuable tool for researchers in the fields of oncology and cell biology. By utilizing this antibody, scientists can gain insight into the function of CEACAM5 and its potential implications in cancer research.
Product Name:
CEACAM5 Rabbit Polyclonal Antibody
SKU:
CAB12421
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-685 of human CEACAM5 (NP_001278413.1).
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1048
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CEACAM5 Rabbit pAb (CAB12421) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
