The CEACAM5 Polyclonal Antibody (CAB0970) is a specialized antibody designed for research involving CEACAM5, a cell surface glycoprotein that is overexpressed in various types of cancer. This antibody is raised in rabbits and is highly reactive with human samples, making it a valuable tool for studying CEACAM5 expression in cancer cells.CEACAM5, also known as carcinoembryonic antigen-related cell adhesion molecule 5, is a biomarker for certain types of cancer, including colorectal cancer and lung cancer. By specifically binding to CEACAM5 protein, this antibody enables accurate detection and analysis of CEACAM5 levels in different cell types, providing valuable insights into cancer biology and progression.
The CEACAM5 Polyclonal Antibody is validated for use in Western blot applications, making it a versatile tool for researchers studying cancer biology and developing novel therapies for cancer treatment. Its ability to target CEACAM5 makes it an ideal choice for investigations into the role of this protein in cancer development and progression, offering new possibilities for therapeutic interventions in the fight against cancer.
Product Name:
CEACAM5 Rabbit Polyclonal Antibody
SKU:
CAB0970
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-702 of human CEACAM5 (P06731).
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1048
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CEACAM5 antibody (CAB0970) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
