The CEACAM3 Polyclonal Antibody (CAB2589) is a valuable tool for researchers studying CEACAM3, a cell surface protein involved in various biological processes, including immune responses. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.CEACAM3, also known as carcinoembryonic antigen-related cell adhesion molecule 3, plays a crucial role in immune surveillance and host defense mechanisms. By targeting CEACAM3, researchers can investigate its functions in immune cell interactions, microbial recognition, and inflammation.
This antibody enables the detection and analysis of CEACAM3 expression in different cell types, making it ideal for studies in immunology, infection biology, and cancer research.Understanding the role of CEACAM3 in immune regulation and disease pathogenesis is essential for developing novel therapeutic strategies for infections, inflammatory disorders, and cancer. The CEACAM3 Polyclonal Antibody is a reliable tool for exploring the functions and mechanisms of CEACAM3, contributing to advancements in biomedical research and drug discovery efforts.
Product Name:
CEACAM3 Rabbit Polyclonal Antibody
SKU:
CAB2589
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human CD66d/CEACAM3 (NP_001806.2).
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
1084
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from A549 cells, using CEACAM3 (CAB2589) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
