The CEACAM21 Polyclonal Antibody (PACO14237) is a vital tool for researchers studying CEACAM21, a cell adhesion molecule known for its role in immune regulation and tumor suppression. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for applications such as Western blotting and immunohistochemistry.CEACAM21 is a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family with known functions in immune response modulation and tumor suppression. Its unique role in regulating cellular interactions and immune responses makes it an attractive target for research in immunology and cancer biology.
This antibody binds specifically to the CEACAM21 protein, enabling researchers to detect and analyze its expression in various cell types.By understanding the function and expression patterns of CEACAM21, researchers can uncover its potential as a therapeutic target for diseases such as cancer and inflammatory disorders. The CEACAM21 Polyclonal Antibody is a valuable tool for investigating the biological roles of CEACAM21 and its implications in disease pathogenesis.
Antibody Name:
CEACAM21 Antibody (PACO14237)
Antibody SKU:
PACO14237
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Fusion protein of human CEACAM21
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO14237(CEACAM21 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14237(CEACAM21 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
Background:
CEACAM21 is a gene which encodes carcinoembryonic antigen.It belongs to the immunoglobulin superfamily-CEA family. Three isoforms of the human protein are produced by alternative splicing.High levels of expression in hematopoietic system, brain and muscle.
CEACAM21: Belongs to the immunoglobulin superfamily. CEA family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Immunoglobulin superfamily; Membrane protein, integralChromosomal Location of Human Ortholog: 19q13.2Cellular Component: integral to membrane
