The CDY1B Polyclonal Antibody (CAB15577) is a valuable tool for researchers studying the CDY1B protein, a key player in various biological processes. This antibody, generated in rabbits, offers high specificity and sensitivity in detecting CDY1B in human samples, making it suitable for use in Western blot applications. By targeting the CDY1B protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for studies in molecular biology and genetics.CDY1B is known for its role in chromatin remodeling and gene regulation, making it a crucial factor in processes such as spermatogenesis and embryonic development.
Its involvement in DNA packaging and transcriptional regulation makes CDY1B a target of interest for researchers exploring mechanisms of gene expression and cellular differentiation. Studying the functions and interactions of CDY1B can provide insights into various biological pathways and potential therapeutic targets in conditions related to fertility or developmental disorders.
Product Name:
CDY1B Rabbit Polyclonal Antibody
SKU:
CAB15577
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human CDY1B (NP_001003895.1).
This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.
Purification Method:
Affinity purification
Gene ID:
253175
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDY1B Rabbit pAb (CAB15577) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
