The CDX2 Rabbit Monoclonal Antibody (CAB19030) is a valuable tool for researchers studying CDX2, a transcription factor involved in intestinal development and differentiation. This antibody, derived from rabbit monoclonal cells, exhibits high specificity and sensitivity towards human CDX2 protein, making it ideal for various research applications such as immunohistochemistry and flow cytometry.CDX2 is known for its role in maintaining the integrity of the intestinal epithelium and regulating the expression of genes involved in gut development.
Dysregulation of CDX2 has been linked to gastrointestinal disorders and certain types of cancers, making it a promising target for therapeutic interventions. By using the CDX2 Rabbit Monoclonal Antibody, researchers can gain insight into the function and expression levels of CDX2 in different cell types and tissues, advancing our understanding of intestinal biology and disease pathology.
Product Name:
CDX2 Rabbit Monoclonal Antibody
SKU:
CAB19030
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDX2 (Q99626).
WB,1:500 - 1:1000 IHC-P,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
CDX3; CDX-3; CDX2/AS; X2
Positive Sample:
SW480,293T
Conjugate:
Unconjugated
Cellular Localization:
Nucleus
Calculated MW:
34kDa
Observed MW:
38kDa
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
Purification Method:
Affinity purification
Gene ID:
1045
Clone Number:
ARC0450
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KD Validated] CDX2 Rabbit mAb (CAB19030) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
