The CDX2 Polyclonal Antibody (CAB1629) is a vital tool for researchers studying the CDX2 protein, a transcription factor that plays a crucial role in the regulation of gene expression in the intestine and other tissues. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications. By binding specifically to the CDX2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in developmental biology, gastrointestinal diseases, and cancer research.CDX2 is known for its involvement in intestinal cell differentiation, with dysregulation of its expression linked to various diseases, including colorectal cancer and inflammatory bowel diseases.
By understanding the functions and regulatory mechanisms of CDX2, researchers can gain valuable insights into the molecular pathways underlying these conditions and potentially identify new therapeutic targets. The CDX2 Polyclonal Antibody is a valuable resource for investigating the role of CDX2 in health and disease, offering a deeper understanding of its implications for human biology and potential therapeutic interventions.
Product Name:
CDX2 Rabbit Polyclonal Antibody
SKU:
CAB1629
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 14-165 of human CDX2 (NP_001256.3).
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
Purification Method:
Affinity purification
Gene ID:
1045
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of Human colon cancer cells using CDX2 Rabbit pAb (CAB1629) at dilution of 1:50 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
