The CDX1 Polyclonal Antibody (CAB5712) is a valuable tool for researchers studying the CDX1 protein, a transcription factor involved in regulating the expression of genes related to cell differentiation and development. This antibody, produced through immunization of rabbits, shows high specificity and sensitivity for human samples, making it suitable for use in Western blotting applications.CDX1 plays a crucial role in the development and maintenance of various tissues, with dysregulation of its expression being linked to diseases such as colorectal cancer and gastrointestinal disorders.
By targeting the CDX1 protein, researchers can gain insights into its function and role in disease pathogenesis, aiding in the development of targeted therapies for these conditions.Overall, the CDX1 Polyclonal Antibody is a valuable tool for researchers investigating the role of CDX1 in cell differentiation and disease, offering reliable detection and analysis capabilities for a variety of research applications.
Product Name:
CDX1 Rabbit Polyclonal Antibody
SKU:
CAB5712
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 136-265 of human CDX1 (NP_001795.2).
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.
Purification Method:
Affinity purification
Gene ID:
1044
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CDX1 antibody (CAB5712) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
