The CDS1 Polyclonal Antibody (CAB13758) is specifically designed for research involving CDS1, a key enzyme involved in lipid metabolism and cell signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the CDS1 protein, this antibody enables the detection and analysis of CDS1 expression in various cell types, making it an essential tool for studies in lipid metabolism, cell signaling, and cancer research.CDS1, also known as CDP-diacylglycerol synthase 1, plays a crucial role in the synthesis of phospholipids, which are essential components of cell membranes.
Dysregulation of CDS1 has been implicated in various diseases, including cancer and metabolic disorders. Understanding the function and regulation of CDS1 is vital for developing targeted therapies for these conditions.Overall, the CDS1 Polyclonal Antibody is a valuable asset for researchers studying lipid metabolism, cell signaling, and cancer biology. Its high specificity and sensitivity make it a reliable tool for investigating the role of CDS1 in health and disease.
Product Name:
CDS1 Rabbit Polyclonal Antibody
SKU:
CAB13758
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human CDS1 (NP_001254.2).
Sequence:
MLEL RHRG SCPG PREA VSPP HREG EAAG GDHE TEST SDKE TDID DRYG DLDS RTDS DIPE IPPS SDRT PEIL KKAL SGLS
Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13.
Purification Method:
Affinity purification
Gene ID:
1040
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDS1 Rabbit pAb (CAB13758) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
