The CDNF Antibody (Paco07383) is a high-quality polyclonal antibody developed for research on CDNF (Cerebral Dopamine Neurotrophic Factor), a neurotrophic factor involved in the protection and repair of dopamine-producing neurons in the brain. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in various applications, including immunofluorescence and immunohistochemistry.CDNF is a promising therapeutic target for neurodegenerative diseases such as Parkinson's disease, as it has shown potential in promoting neuronal survival and function.
Research on CDNF can lead to the development of novel treatments for neurodegenerative disorders and improve our understanding of neuronal maintenance and repair mechanisms.By using the CDNF Antibody (Paco07383), researchers can effectively study the expression and localization of CDNF in different experimental models, contributing to advancements in neurobiology and potential therapeutic interventions for neurological conditions. This antibody is a valuable tool for scientists investigating the role of CDNF in neuroprotection and neuroregeneration processes.
Antibody Name:
CDNF Antibody (PACO07383)
Antibody SKU:
PACO07383
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:10000-1:20000, IHC-p:1:50-1:300
Species Reactivity:
Human
Immunogen:
Synthetic peptide from human protein at AA range: 31-80
Form:
Liquid
Storage Buffer:
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Purification Method:
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200.
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200.
ARMETL1: Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. Belongs to the ARMET family. 2 isoforms of the human protein are produced by alternative splicing.
