CDKN2D Rabbit Polyclonal Antibody (CAB6556)
- SKU:
- CAB6556
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CDKN2D Rabbit Polyclonal Antibody |
SKU: | CAB6556 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human CDKN2D (NP_001791.1). |
Sequence: | MLLE EVRA GDRL SGAA ARGD VQEV RRLL HREL VHPD ALNR FGKT ALQV MMFG STAI ALEL LKQG ASPN VQDT SGTS PVHD AART GFLD TLKV LVEH GADV NVPD GTGA LPIH LAVQ EGHT AVVS FLAA ESDL HRRD ARGL TPLE LALQ RGAQ DLVD ILQG HMVA PL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | p19; INK4D; p19-INK4D; CDKN2D |
Positive Sample: | Jurkat,K-562(Low expression control) |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 18kDa |
Observed MW: | 18kDa |
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.
Purification Method: | Affinity purification |
Gene ID: | 1032 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |